The file contains experimental detail overview, data legend and Thermal Proteome Profiling dataset from Hazara virus infected SW13 cells treated with DMSO or antiviral inhibitor 20 µM TH6744.The raw MS/MS data was searched against the UniProt Homo Sapiens database (containing canonical and isoforms_42144 entries downloaded on March 21st 2016) using Mascot. Summarized are a list of proteins identified in each replicate and experimental condition.