# Consiglio et al 2020 Cell The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19 ## General info Publication: "The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19" This project used multiple omics data: - Plasma protein expression (Olink - NPX values) - FACS - Autoantibodies ## Data description - ```TableS1-xlsx``` Supplementary Table 1 Plasma Protein Levels in Median NPX value (Standard Deviation) in Adults and Children COVID-19 Infection, MIS-C, and Kawasaki Disease, Related to Figure 2. - ```TableS2-xlsx``` Supplementary Table 2 Plasma Protein Levels in Median NPX value (Standard Deviation) in Healthy Children, SARS-CoV-2 Infected with Mild Infection, Children with MIS-C, and Kawasaki Disease, Related to Figure 4. - ```TableS3-xlsx``` Supplementary Table 3 Normalized Autoantibody Binding across 9,341 Autoantigens for Each of the 56 Indicated Plasma Samples, Related to Figure 7. - ```OlinkMay1.xlsx``` Olink table (figures 2, 4 and 5) Plasma Protein Levels (NPX value) from first batch of samples from Healthy Children SARS-CoV-2 Infected with Mild Infection, Children with MIS-C, and Kawasaki Disease. - ```OlinkJuly1.xlsx``` Olink table (figures 2, 4 and 5) Plasma Protein Levels (NPX value) from second batch of samples from Healthy Children SARS-CoV-2 Infected with Mild Infection, Children with MIS-C, and Kawasaki Disease. - ```Petter_Brodin_Covid-19_Plate1_NPX_LOD.xlsx``` Olink table (figure 2) Plasma Protein Levels (NPX value) from samples from SARS-CoV-2 infected adults (plate 1). - ```Petter_Brodin_Covid-19_Plate2_NPX_LOD.xlsx``` Olink table (figure 2) Plasma Protein Levels (NPX value) from samples from SARS-CoV-2 infected adults (plate 2). - ```CD57_Dataset.txt``` Flow cytometry data (figure 3) Frequency of CD57+ cells in Healthy Children, SARS-CoV-2 Infected with Mild Infection, Children with MIS-C, and Kawasaki Disease. - ```Dataset_CleanAll.txt``` Flow cytometry data (figure 3) Lymphocyte frequencies in Healthy Children, SARS-CoV-2 Infected with Mild Infection, Children with MIS-C, and Kawasaki Disease. - ```Figure4-ID.csv``` SampleID table (figure 4) Sample labels from Healthy Children, SARS-CoV-2 Infected with Mild Infection, Children with MIS-C, and Kawasaki Disease. - ```Figure5-ID.csv``` SampleID table (figure 5) Sample labels from Healthy Children, SARS-CoV-2 Infected with Mild Infection, Children with MIS-C, and Kawasaki Disease. - ```filtered-scores.csv``` VirScan scores table (figure 6) VirScan scores from Healthy Children, SARS-CoV-2 Infected with Mild Infection, Children with MIS-C, and Kawasaki Disease. - ```filtered-scores-label.csv``` VirScan labels table (figure 6) VirScan labels from Healthy Children, SARS-CoV-2 Infected with Mild Infection, Children with MIS-C, and Kawasaki Disease. - ```MIS_C.Experiment.QuantileNormailized.200712.csv``` Autoantibody table (figure 7) Autoantibody profile of Healthy Children, SARS-CoV-2 Infected with Mild Infection, Children with MIS-C, and Kawasaki Disease. - ```Figure7-ID.csv``` SampleID table (figure 7) Sample labels from Healthy Children, SARS-CoV-2 Infected with Mild Infection, Children with MIS-C, and Kawasaki Disease. - ```ELISA.xlsx``` ELISA table (figure 7) Plasma endoglin levels determined by ELISA from Healthy Children, SARS-CoV-2 Infected with Mild Infection, Children with MIS-C, and Kawasaki Disease.