Minjun Yang

Publications

• EsrB negatively regulates expression of the glutamine sythetase GlnA in the fish pathogen Edwardsiella piscicida
• Genetic predisposition to B-cell acute lymphoblastic leukemia at 14q11. 2 is mediated by a CEBPE promoter polymorphism
• Fine mapping MHC associations in Graves’ disease and its clinical subtypes in Han Chinese
• Identification of Targetable Lesions in Anaplastic Thyroid Cancer by Genome Profiling
• Proteogenomics and Hi-C reveal transcriptional dysregulation in high hyperdiploid childhood acute lymphoblastic leukemia
• A urinary extracellular vesicle microRNA biomarker discovery pipeline; from automated extracellular vesicle enrichment by acoustic trapping to microRNA sequencing
• Global RNA Expression and DNA Methylation Patterns in Primary Anaplastic Thyroid Cancer
• 13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking
• Sister chromatid cohesion defects are associated with chromosomal copy number heterogeneity in high hyperdiploid childhood acute lymphoblastic leukemia.
• Single base substitution mutational signatures in pediatric acute myeloid leukemia based on whole genome sequencing
• Sensor histidine kinase is a $β$-lactam receptor and induces resistance to $β$-lactam antibiotics
• Characterization of somatic mutations in air pollution-related lung cancer
• Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10p21. 2
• Genomic complexity and targeted genes in anaplastic thyroid cancer cell lines
• Whole genome sequencing revealed host adaptation-focused genomic plasticity of pathogenic Leptospira
• Characterization of immune cells and perforin mutations in familiar venous thromboembolism
• Genome analysis and in vivo virulence of porcine extraintestinal pathogenic Escherichia coli strain PCN033
• A $σ$E-mediated temperature gauge controls a switch from LuxR-mediated virulence gene expression to thermal stress adaptation in Vibrio alginolyticus
• Negative feedback-defective PRPS1 mutants drive thiopurine resistance in relapsed childhood ALL
• Transcriptomic dissection of the horizontally acquired response regulator EsrB reveals its global regulatory roles in the physiological adaptation and activation of T3SS and the cognate effector repertoire in Edwardsiella piscicida during infection toward turbot
• Edwardsiella comparative phylogenomics reveal the new intra/inter-species taxonomic relationships, virulence evolution and niche adaptation mechanisms
• Proteomic analysis of a twin-arginine translocation-deficient mutant unravel its functions involved in stress adaptation and virulence in fish pathogen Edwardsiella tarda
• Complete genome sequence of Pasteurella multocida HN06, a toxigenic strain of serogroup D
• Transcriptome profiling reveals Th17-like immune responses induced in zebrafish bath-vaccinated with a live attenuated Vibrio anguillarum
• Phylogenetic investigation of Edwardsiella tarda with multilocus sequence typing (MLST) and pulsed field gel electrophoresis (PFGE) typing methods
• ContigScape: a Cytoscape plugin facilitating microbial genome gap closing
• A transcriptome analysis suggests apoptosis-related signaling pathways in hemocytes of Spodoptera litura after parasitization by Microplitis bicoloratus
• Draft genome sequence of an anaerobic, thermophilic bacterium, Thermoanaerobacterium aotearoense SCUT27, isolated from a hot spring in China
• Edwardsiella tarda flagellar protein FlgD: a protective immunogen against edwardsiellosis
• An Edwardsiella tarda mutant lacking UDP-glucose dehydrogenase shows pleiotropic phenotypes, attenuated virulence, and potential as a vaccine candidate
• Genome-wide expression analysis in Down syndrome: insight into immunodeficiency
• Identification of qseEGF genetic locus and its roles in controlling hemolytic activity and invasion in fish pathogen Edwardsiella tarda
• QseBC controls flagellar motility, fimbrial hemagglutination and intracellular virulence in fish pathogen Edwardsiella tarda
• RNA-seq liver transcriptome analysis reveals an activated MHC-I pathway and an inhibited MHC-II pathway at the early stage of vaccine immunization in zebrafish
• Characterization of two TonB systems in marine fish pathogen Vibrio alginolyticus: their roles in iron utilization and virulence
• Genome sequence of the versatile fish pathogen Edwardsiella tarda provides insights into its adaptation to broad host ranges and intracellular niches